Tag: antimicrobial resistance

RAPID-Test trial completes recruitment early

Posted on by capcbristol

A major clinical trial investigating whether GP use of rapid diagnostic tests for respiratory (chest) infections can reduce same-day antibiotic prescribing in primary care has completed recruitment early.

Home testing for respiratory infection as mum puts swab into the nose of her son sitting on a kitchen desk.

The RAPID-TEST trial, led by Professor Alastair Hay at the Centre for Academic Primary Care, University of Bristol, originally aimed to complete recruitment of 514 patients by September 2024. With enormous interest in the trial from GP practices across the Bristol, Bath, Swindon, North/North East Somerset, South Gloucestershire, Gloucestershire and Wiltshire areas, the target was met five months early.

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Call to reduce repeat ‘within-episode’ antibiotic prescriptions for respiratory tract infections in primary care

Posted on by capcbristol

A new study exploring the use of repeat antibiotic prescriptions for the same respiratory tract infection (RTI) episode – known as repeat ‘within-episode’ prescriptions – in primary care has found high rates of their use in England, despite evidence that they are of little benefit. The study authors, from the Universities of Bristol and Bath, King’s College London, and University Medical Center Utrecht, are calling for a reduction in their use and to make them a target for antimicrobial stewardship interventions.

Pills scattered on a white table top next to a white pill container.

RTIs are one of the most common reasons people visit a GP in the UK. Many RTIs are caused by viruses and current primary care guidelines recommend a no or delayed antibiotic prescribing strategy in the vast majority of patients. Despite this, 54% of RTI consultations in UK primary care result in an antibiotic prescription, and RTIs account for 60% of antibiotic prescribing in primary care worldwide. As such, RTIs are one of the key drivers of antimicrobial resistance.

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